An efficient system
to treat ovarian follicular cysts in cattle has been developed.
In this system, a GnRH agonist is injected to luteinize the cyst
and induce recruitment and selection of a new follicle. At the time
of GnRH agonist treatment, an intravaginal progesterone device is
inserted to reduce the endogenous pulsatility of LH. On day 7 after
insertion of the intravaginal progesterone device, an injection
of PGF2α is given to regress any induced CL formed
from an active subordinate follicle present at the time of GnRH
agonist treatment. The intravaginal progesterone device is removed
on day 9 after insertion and cows express estrus on day 11. Associated
with the induced estrus is a normal ovulation and subsequent CL
development with re-occurring follicular waves throughout the estrous
cycle. Thus successful treatment is completed within a 11 day period.